Authors: NOOF ATYAH ALI ALHARTHY & Prof. Dr. EBTISAM ABDULLAH BAWAZIR
Company/Faculty/School: Department of Biology, Faculty of Science, Jeddah University, Jeddah, Saudi Arabia
Country: Saudi Arabia
e-mail: NAALHARTE@uj.edu.sa / firstname.lastname@example.org
Alzheimer disease is a neurodegenerative disease that cause progressive impairment of brain cognitive functions. The study defines neural effects of mixture Figs (Ficus carica) and Olive oil as herbal plants to relieve the cholinergic abnormality and oxidative stress in amnesia induced by Scopolamine as a model of Alzheimer’s disease in hippocampus of male Albino Rats. The rats were divided into five equal groups : first group was the control, the second received a dose of mixture dried Figs and Olive oil orally, third produced memory deficits by scopolamine, fourth was treated with mixture of Figs and Olive oil followed by scopolamine, fifth was given dose of Rivastigmine and Scopolamine. At the end of the experiment: the changes of behavioural activities and acetylcholinesterase AchE levels in the rats were investigated. The administration of the mixture Figs and Olive oil resulted in enhancement of behavioural activities and reduction in the AchE due to the antioxidant properties.