The Ameliorative Effect of Phellinus linteus mycelium on Muscle Atrophy

Authors: Chen Chin-Chu; Li I-Chen; Li Tsung-Ju; Chen Yen-Po

Company/Institution: GRAPE KING BIO

Country: Taiwan

e-mail: eddie@wiipa.org.tw

web: https://www.wiipa.org.tw/

Sarcopenia is a potential healthcare crisis in elderly population. We found that the Phellinus linteus mycelium has the potential to prevent myotube atrophy from dexamethasone damage. Next, we performed cast immobilization (IM) on mice as our in vivo muscle atrophy animal model. The IM mice were fed at beginning of the trial with Phellinus linteus mycelium. Muscle endurance and grip strength showed significantly improvement when compared with the control after two weeks. The result showed that supplementation of Phellinus linteus mycelium has ameliorative effect on IM induced muscle atrophy.