MANUFACTURING PROCESS OF A PRODUCT DESTINED FOR BONE DEFECTS RECONSTRUCTION, BASED ON HYDROXIAPATITE AND BIOGENIC BIPHASIC CALCIUM PHOSPHATE
Authors: Florin MICULESCU, Aura MOCANU, George STAN, Iulian ANTONIAC, Mihnea Cosmin COSTOIU, Stefan VOICU, Marian MICULESCU, Ileana MATES, Augustin SEMENESCU
Company/Faculty/School: University POLITEHNICA of Bucharest
Country: ROMANIA
e-mail: asemenescu2002@yahoo.com
web: https://www.pub.ro
The invention relates to the manufacturing process of a product destined for bone defects reconstruction, based on hydroxyapatite and biogenic biphasic calcium phosphate, with a controlled ratio between hydroxyapatite/tricalcium phosphate. All calcium phosphates result from the thermal dissociation of calcium carbonate in form of dolomitic marble and seashells, and treatment of calcium hydroxide solution with phosphoric acid (range: 100−130% x calculated stoichiometric amount).
