Author: ANITA ŠALIĆ, MARKO BOŽINOVIĆ, IVAN KARLO CINGESAR, DOMAGOJ VRSALJKO, BRUNO ZELIĆ
Company/Institution: Fakultet kemijskog inženjerstva i tehnologije
Country: Croatia
e-mail: asalic@fkit.unizg.hr; marko.bozinovic@fkkt.uni-lj.si; icingesar@fkit.unizg.hr; dvrsal@fkit.unizg.hr; bzelic@fkit.unizg.hr
web: https://www.fkit.unizg.hr/
The reduction in size and the specific performance of micro- and millistructured devices have led to numerous advantages and expanded their application possibilities compared to existing macroscopic systems. Small dimensions increase the multifunctionality of the entire system, as several physico-chemical processes: reactions, separation and analysis, can take place simultaneously in one cell. The innovation of the integrated micro/milli system for continuous extraction of macromolecules lies in its ability to combine the best features of microextractors and milliseparators in a unique platform. This integrated system enables the simultaneous application of microsystem for the fast and efficient extraction of macromolecules and use of millisystem for the precise and continuous separation of extract and raffinate phase. In addition, the integration of the two processes enables continuous sample processing without interruptions, resulting in improved productivity and shorter processing time. This results in higher process efficiency with minimal losses and resource consumption, making this system attractive for various applications in biotechnology, production of pharmaceuticals and other industries.