Extended release formulation for parenteral use aimed at alleviating pain in arthritis patients

The developed formulation consists of a biocompatible and biodegradable polymer system, a biocompatible solvent, and a non-steroidal anti-inflammatory drug (NSAID). The formulation is intended for local application, such as to the knee, where a polymer hydrogel forms and ensures the drug is released according to a given therapeutic profile over a longer period of time. This method of administration ensures the drug is available locally at the source of pain. It avoids the gastrointestinal tract, where chronic conditions can result from long-term oral administration. It reduces the frequency of administration and increases drug usability, allowing for lower drug consumption.