Development of Nano-PCR Diagnostic Kit for Human Papillomavirus (HPV)
Authors: Mohammad Panji, Elahe Motevaseli, Mohammad Hossein Modarressi, Zahra Azizi Varzaneh, Moloud Absalan
Company/Institution: Department of Molecular Medicine, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran; Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
Country: IRAN
Web: www.irtopinventors.com
The Nano-PCR diagnostic kit for Human Papillomavirus (HPV) combines nanotechnology and molecular medicine to deliver a highly sensitive and cost-effective tool for early detection. Unlike conventional PCR kits, which often miss low viral loads, and expensive imported kits, this innovation uses gold nanoparticles to enhance primer–DNA binding, improve amplification efficiency, and reduce nonspecific signals. Clinical results show detection rates above 95% in early-stage samples, compared to 75% with standard PCR. The kit is faster, more affordable, scalable, and capable of detecting multiple high-risk HPV strains simultaneously. Designed for diagnostic labs, cancer prevention centers, and large-scale screening, it reduces reliance on costly imports while increasing accessibility to advanced HPV testing. Overall, this invention represents a transformative step in early cancer prevention and public health.
